systemic circulation

Concept: The fraction of unchanged drug reaching systemic circulation following administration by any route.

经任何给药途径给予一定剂量的药物后到达全身血循环内药物的百分率.

Bioavailability expresses the extent of drug absorption into the systemic circulation.

生物利用度表示药物吸收进入体循环的分量.

The immunosuppressive agent cyclophosphamide not only increased the rate of bacterial translocation into MLN and the number of living bacteria in MLN, but also promoted bacteria to spread into the systemic circulation.

免疫抑制剂环磷酰胺不仅增加肠梗阻时肠菌移位的发生率（100%∶80%），且使更多的肠菌存活于MLN中并向体循环内播散。

It is directly proportional to the total amount of unchanged drug that reaches the systemic circulation.

它直接与到达体循环的原形总药量成正比.

Lipo-PGE1 showed no significant effect on systemic circulation pressure and heart rate. Regitine showed significant effect on hemodynamics which decreased the pressure of systemic circulation and increase heart rate significantly ( P < 0.01).

前列地尔对体循环压力和心率影响不明显，而酚妥拉明使体循环压力下降，并明显加快心率（P均<0.01），对患者血流动力学影响较大。

Conclusion Inhaled nebulized DETA/ NO adduct could significantly improve early allograft lung function and had no significant effect on the systemic circulation.

结论雾化吸入DETA/NO能有效地改善移植肺早期肺功能，且对体循环无明显影响。

Causes of disease for salvage were as follows: 50 cases of circulation system, 133 of respiration system ( including 34 heavy hemoptysis and 40 tension pneumothorax), 12 of central nerve system disease, 5 intoxication and 31 other systemic diseases.

呼吸系统方面133例（其中大咯血34例，张力性气胸40例等）；中枢神经系统疾病12例；